NanoCommons Molecular Initiating Event (MIE) Prediction Tool and MIE-Gene Signatures Database
Using published data from in vivo and in vitro experimental studies of nanomaterials toxicity and different signaling and functional databases, the NanoCommons Molecular Initiating Events (MIE) gene set database (NanoCommons GS-MIE DB) captures gene signatures (GS) of MIEs by integrating knowledge from KEGG, REACTOME, GO, WikiPathways public databases and custom gene sets from published data. To date, 132 gene sets representing three different types of MIE actions have been manually collected and via a user friendly interface can be used to calculate a prioritized list of MIEs with identified biological processes triggered by exposure to nanomaterials.
Link to D6.7 once finalised. Training materials in preparation also....
The NanoCommons Transnational Access (TA) is the ability of nanosafety researchers from industry, academia and regulatory bodies to access the state-of-the-art NanoCommons expertise free of charge and take advantage of the NanoCommons services, facilities and knowledge to advance their work, solve problems and take their research to the next level.Back to all services